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SF3B1-targeted Splicing Inhibition Triggers Global Alterations in transcriptional Dynamics and R-Loop Metabolism

Daisy Castillo-Guzman, Stella R. Hartono, Lionel A. Sanz, et al.

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Jean Farup, Jesper Just, Frank de Paoli, et al.

Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes

Radoslaw P. Kozak, Karina Mondragon-Shem, Christopher Williams, et al.

Discussion

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

Discussion

Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway

M. Elizabeth Deerhake, Keiko Danzaki, Makoto Inoue, et al.

Discussion

Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomes

Michael Mitter, Catherina Gasser, Zsuzsanna Takacs, et al.

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.

Discussion

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Discussion

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8⁺ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.

Discussion

The nuclear to cytoplasmic ratio directly regulates zygotic transcription in Drosophila

Henry Wilky, Sahla Syed, João Raimundo, et al.

Single-cell RNA-sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann, Austin J. Gutierrez, Linh T. Bui, et al.

AND

Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis

Taylor S. Adams, Jonas C. Schupp, Sergio Poli, et al.

Dynamics of Meiotic Sex Chromosome Inactivation and Pachytene Activation in Mice Spermatogenesis

Ábel Vértesy, Javier Frias-Aldeguer, Zeliha Sahin, et al.